改良冷刀锥切与LEEP刀治疗宫颈高级别上皮内瘤样病变的疗效比较

Comparison of the efficacy of modified cold knife cone and LEEP in the treatment of high-grade cervical intraepithelial neoplasia

目的探析改良冷刀锥切与LEEP刀治疗宫颈高级别上皮内瘤样病变的疗效。方法选取我院2013年1月~2014年1月收治的宫颈高级别上皮内瘤样病变患者120例,随机分为观察组和对照组,观察组患者采用改良冷刀锥切术治疗,对照组患者采用LEEP刀治疗,观察对比两组患者的疗效。结果观察组患者手术治疗平均时间为(20.7±6.2)min,术中出血量为(36.7±5.4)mL;对照组患者手术治疗平均时间为(11.2±3.4)min,术中出血量为(10.8±2.7)mL,观察组明显高于对照组,差异有统计学意义(P<0.05)。观察组患者术后出血率为4%,对照组患者术后出血率为13%,观察组明显低于对照组,差异有统计学意义(P<0.05)。结论改良冷刀锥切与LEEP刀治疗宫颈高级别上皮内瘤样病变具有不同优势,临床中应注意结合患者特点合理选择和应用。

Objective To study the effect of modified cold knife cut and LEEP in the treatment of high- grade cervical intraepithelial neoplasia. Methods 120 patients with high grade cervical intraepithelial neoplasia in our hospital from January 2014 to January 2013 were randomly divided into two groups. The observation group were treated with modified cold knife cone resection, the control group was treated with LEEP, and the efficacy of the two groups were observed and compared. Results The average time of operation was （20.7±6.2） min, the amount of bleeding in the observation group was （36.7±5.4） mL; the average time of the control group was （11.2±3.4） rain, the amount of bleeding was （10.8±2.7） mL, the observation group was significantly higher than the control group, The difference was statistically significant（P〈0.05）. In addition, the bleeding rate was about 4% in the observation group, the control group was about 13%, the observation group was significantly lower than the control group, The difference was statistically significant（P〈0.05）. Conclusion Modified cold knife cone resection and LEEP in the treatment of high-grade cervical intraepithelial neoplasia have different advantages. Doctors should accord to the character^sties of oatients to select.