摘要
目的 通过检测尿液中微量白蛋白（Alb）、肌酐（Cr）、尿微量白蛋白/尿肌酐比值（ACR）、血液CRP和Hb A1C,分析测定数据的变化,探讨它们与糖尿病性肾病（DN）的关系及诊断价值。方法 抽取2013年1月~2014年8月收治的60例糖尿病性肾病患者为观察组,并选取同期60例健康体检者为对照组,分别进行尿微量白蛋白、肌酐、ACR比值进行检测;同时检测糖化血红蛋白、CRP。结果 与对照组相比,观察组ACR比值灵敏性最佳,同时血液CRP和Hb A1C明显升高,差异有显著性意义（P〈0.01）。结论 血液CRP和Hb A1C、尿液ACR比值对糖尿病早期肾损伤的敏感性高,为糖尿病性肾病早期及时诊断提供更为方便可靠的重要指标。
Objective To detect the markers of Alb, Cr, ACR, CRP, and HbA1C and analyze the change of the measured data. The aim of the study was to explore the correlation and the diagnosis value of the markers and DN. Methods 60 cases of DN in our hospital were chosen as treatment group, and 60 cases physical examination patients were as control. The Alb, Cr, ACR, CRP and HbA1C were analyzed. Results Compared with control, the ACR of treatment group were more sensitiveness. Besides, serum CRP and HbA1C were significantly elevated （P 〈 0. 01 ）. Conclusion Serum CRP, HbA1C and urine ACR were sensitive to diabetes early renal damage, and can be used as markers for timely diagnosis of DN.
出处
《现代医院》
2016年第1期59-61,共3页
Modern Hospitals
