期刊文献+

颈动脉易损斑块MRI表现与缺血性脑卒中的风险预测 被引量:16

MRI appearances of carotid vulnerable plaques and prediction of the risk of ischemic stroke
下载PDF
导出
摘要 目的应用磁共振高分辨率成像技术,探讨颈动脉易损斑块MR表现与缺血性脑卒中风险预测。材料与方法经B超检查筛选颈动脉斑块并行颈部血管磁共振检查的200例老年患者,颈动脉斑块分稳定斑块组和易损斑块组,分析两组斑块成分(脂质核团,脂质坏死核心,斑块内出血,钙化,纤维帽是否破裂)及管腔狭窄程度,随访60 d内发生缺血性脑卒中的患者。结果稳定斑块组112例,60 d内发生缺血性脑卒中的患者2例;易损斑块组88例,60 d内发生缺血性脑卒中26例。结论颈动脉易损斑块与60 d内发生缺血性脑卒中有显著相关性,可以作为颈动脉狭窄患者近期临床症状的预测指标。 Objective: To study the correlation between the MRI appearances of carotid vulnerable plaque and the risk of ischemic stroke by application of magnetic resonance imaging in high resolution imaging. Materials and Methods: Two hundred cases of carotid plaques were screened by B ultrasound examination and were performed Cervical vascular magnetic resonance imaging. Carotid plaques were divided into stable plaque group and vulnerable plaque group, then we analysed the plaque composition and the degree of luminal stenosis. Patients were followed up for 60 days with the occurrence of ischemic stroke. Results: Stable plaque group 112 cases, 2 cases of ischemic stroke occurred within 60 days. Vulnerable plaque group 88 cases, 26 cases of ischemic stroke occurred within 60 days. Conclusions: There was a significant correlation between carotid vulnerable plaque and ischemic stroke within60 days. Carotid vulnerable plaque can be used as a predictor of short-term clinical symptoms in patients with carotid artery stenosis.
作者 李红英
出处 《磁共振成像》 CAS CSCD 2016年第1期16-19,共4页 Chinese Journal of Magnetic Resonance Imaging
关键词 颈动脉狭窄 脑缺血 磁共振成像 Carotid stenosis Brain ischemia Magnetic resonance imaging
  • 相关文献

参考文献3

二级参考文献104

  • 1Ross R.Atherosclerosis-an inflammatory disease,1999.
  • 2Schoenhagen P;Ziada KM;Kapadia SR.Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study,2000.
  • 3Botnar RM;Stuber M;Kissinger KV.Noninvasive coronary vessel wall and plaque imaging with magnetic resonance imaging,2000(102).
  • 4Mann JM,Davies MJ.Vulnerable plaque: relation of characteristics to degree of stenosis in human coronary arteriesCirculation,1996.
  • 5Kelly K A,Allport J R,Tsourkas A,et al.Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circulation Research . 2005
  • 6Winter PM,Morawski AM,Caruthers SD,et al.Molecular imaging of angiogenesis in early-stage atherosclerosis with alpha(v)beta3-integrin-targeted nanoparticles. Circulation . 2003
  • 7Virmani R,Kolodgie FD,Burke AP,et al.Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arteriosclerosis . 2000
  • 8Ambrose J A,Tannenbaum M A,Alexopoulos D,et al.Angiographic progression of coronary artery disease and the development of myocardial infarction. Journal of the American College of Cardiology . 1988
  • 9Sirol VM,Itskovich V,Mani V,et al.Lipid-rich atherosclerotic plaques detected by gadofluorine-enhanced in vivo magnetic resonance imaging. Circulation . 2004
  • 10Juan C Frias,Kevin Jon Williams,Edward A Fisher.Recombinant HDL-Like Nanoparticles: A Specific Contrast Agent for MRI of Atherosclerotic Plaques. Journal of the American Chemical Society . 2004

共引文献28

同被引文献117

  • 1林凯,张兆琪,吕飚.颈动脉壁易损斑块与再发缺血性脑卒中间隔时间关系的磁共振研究[J].中国医学影像技术,2006,22(3):372-376. 被引量:9
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33022
  • 3Liu L, Wang D, Wong KS, et al. Stroke and stroke care in China: huge burden, significant workload, and a national priority. Stroke, 2011, 4202): 3651-3654.
  • 4Mostaza JM, Martin-Jadraque R, Vicente I, et al. Patients at high risk of cerebrovascular disease: the REACH study. Cerebrovascular Diseases, 2009, 27(Suppl): 77-81.
  • 5Diener HC, Ringleb PA, Savi P. Clopidogrel for the secondary prevention of stroke. Expert Opinion on Pharmacotherapy, 2005, 6(5): 755-764.
  • 6Hamer M, Chida Y, Stamatakis E. Association of very highly elevated C-reactive protein concentration with cardiovascular events and all-cause mortality. Clinical Chemistry, 2009, 56(1): 132-135.
  • 7Lindsay AC, Biasiolli L, Lee JMS, et al. Plaque features associated with increased cerebral infarction after minor stroke and TIA: a prospective, case-control, 3-T carotid artery MR imaging study. JACC Cardiovascular lmaging, 2012, 5(4): 388-396.
  • 8Harrison JK, Sloan B, Dawson J, et al. The ABCD and ABCD2 as predictors of stroke in transient ischemic attack clinic outpatients: a retrospective cohort study over 14 years. Qjm Monthly Journal of the Association of Physicians, 2010, 103(9): 679-685.
  • 9Liu X, Zhao H, Cao Y, et al. Comparison of carotid atherosclerotic plaque characteristics by high-resolution black-blood MR imaging between patients with first-time and recurrent acute ischemic stroke. AJNRAm J Neuroradiol, 2012, 33(7): 1257-1261.
  • 10Wattanakit K, Folsom AR, Chambless LE, et al. Risk factors for cardiovascular event recurrence in the Atherosclerosis Risk in Communities (ARIC) study. American Heart Journal, 2005, 149(4): 606-612.

引证文献16

二级引证文献134

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部