《丹溪心法》治疗脾胃病方剂用药特点分析

Analysis on the Medication Features in the Treatment of Spleen-stomach Disorders in Dan Xi Xin Fa

目的应用数据挖掘技术分析《丹溪心法》治疗脾胃病方剂用药特点,为临床治疗脾胃病提供参考。方法以《丹溪心法》为检索源,采集朱丹溪治疗脾胃病的相关方剂,按照统一标准加以人工干预和规范处理。利用频数统计确定治疗脾胃病的常用药物。通过建立共现矩阵、聚类和网络可视化分析常用药物的配伍特点和相互关系。结果共纳入处方105首,涉及中药150种。炙甘草、陈皮、白术、人参、茯苓等17种中药是治疗脾胃病的常用药物。结论朱丹溪在治疗脾胃疾病时重视补益脾胃,尤其重视清养脾胃,养胃气,益阴精;用药主要以甘温补气为主,辅以辛、苦之药以行气祛湿。

Objective To investigate the medication features in the treatment of spleen-stomach disorders in Dan Xi Xin Fa; To provide references for the clinical treatment of relevant diseases. Methods Dan Xi Xin Fa was set as retrieval source. The prescriptions about treating spleen-stomach disorders in the book of Dan Xi Xin Fa was retrieved, which were under standardized artificial intervention and process. The frequency statistics was adopted to analyze the highly-used medicines, and co-occurrence matrix, clustering and network visualization were used to analyze the compatibility features and relationship among the medicines. Results 105 prescriptions were collected, and 150 Chinese medicinal materials were involved. 17 Chinese medicinal materials including Glycyrrhizae Radix et Rhizoma, Cirri Reticulatae Pericarpium, Atractylodis Macrocephalae Rhizoma, Ginseng Radix et Rhizoma and Poria were commonly used Chinese medicinal materials in the treatment of spleen- stomach disorders. Conclusion Zhu Danxi laid his emphasis on tonifying spleen and stomach in the treatment of spleen-stomach disorders, especially on clearing the spleen and stomach, nourishing stomach qi and tonifying yin essence. It is Zhu Danxi＇s medication features in the treatment of spleen-stomach disorders to tonify qi with sweetish taste and warm medicines, and promote qi circulation and eliminate dampness by hot and bitter taste ones.