复方板黄口服液制备工艺研究

Study on Preparation Technology of Compound Banhuang Oral Liquid

为确定复方板黄口服液的最佳制备工艺,采用正交试验等方法,对复方板黄口服液制备工艺各条件进行优选。确定的最佳工艺为药材加纯净水浸渍12h,煎煮2次,每次1h,滤液80℃浓缩至药液相对密度为1.18g生药/mL^1.25g生药/mL,醇沉2次(含醇量分别为600mL/L和750mL/L),静置24h,回收乙醇,加纯净水定容。该制备工艺简便易行,质量稳定,可作为复方板黄口服液的最佳制备工艺。

To define the optimal conditions of preparation technology of Banhuang compound oral liquid, the conditions were screened by using some methods such as orthogonal test. The optimum conditions are as follows： soaking time of the medicinal is 12 h, decoction time is 1 h for twice, the relative density of the concentrated solution is 1.18 g/mL-1.25 g/mL, ethanol precipitating twice and the density of the ethanol precipitation is 600 mL/L and 750 mL/L respectively, standing time is 24 h. The results of the optimizated preparation process showed that the preparation process of Banhuang oral liquid is stable, simple and suit- able for prepartion.