慢性肾脏病患者心血管事件相关预测因子

Predictors of Cardiovascular Event in Patients with Chronic Kidney Disease

慢性肾脏病(CKD)患者逐年增加,心血管疾病作为其最主要的并发症,决定着CKD患者的预后。尽管目前临床医师已经对CKD患者进行了相对全面的检查,并已经使用药物对心脏功能进行早期的干预性治疗,但CKD患者心血管疾病并发症仍有很高的发生率及病死率。CK不仅仅是一个临床问题,肾脏替代治疗消耗大量的医疗资源,患者生活质量大大下降。近年来,心血管学科和肾脏学科医师强烈推荐,评估肾脏功能应该是心血管疾病患者诊断的一部分,同时肾脏病患者也应早期完善心血管疾病的相关检查。传统的心血管事件的危险因素对于预测CKD患者早期心血管事件风险似乎并不十分准确及全面,一些非传统性的因素,例如炎性介质及电解质近年来备受关注。

The number of patients with chronic kidney disease is increasing with years,and cardiovascular disease, as the main complication, determines the prognosis in patients with chronic kidney disease （CKD）. Ahhoughrelatively comprehensive checkups of the CKD patients have been performed in clinical, and drugs have been used as early intervention treatment on cardiac function, the cardiovascular complications in CKD patients still have a high incidence and a high mortality. CKD is not just a clinical problem, and renal replacement therapy consumes a lot of medical resources, and the quality of life of CKD patients is greatly reduced. In recent years, cardiovascular and kidney discipline physicians strongly recommended that assessing renal function should be a part of the diagnosis of cardiovascular disease in patients, and in patients with kidney diseases early examination of cardiovascular disease should be improved. The traditional risk fac- tom to predict the risk of cardiovascular events seem to be inaccurate and incomprehensive in patients with chronic kidney disease. Some non-traditional factors, such as inflammatory mediators and electrolyte, have attracted much attention in recent years.