青光眼眼底形态学构建及研究

The Fundus Morphological Construction and Research of Glaucoma

青光眼是一种不可逆的致盲性眼病,其发病机制尚未完全明了。筛板是青光眼视神经轴突损害的初始位置,筛板形态的改变与青光眼病程进展有关。光学断层相干扫描技术(OCT)是一种无创性可观察活体视网膜结构的图像采集技术,可被应用于观察眼球的深部结构。深度型频域OCT(EDI-OCT)与图像处理技术结合,可清晰观察青光眼的眼底形态及量化筛板的相关结构,对诊断、治疗青光眼具有重要意义。

Glaucoma is an irreversible eye blinding disease, the pathogenesis of which has not been fully understood yet. The laminar region is recognized as the primary position of optic nerve axon damage in glau- coma. The changing of laminar morphology is regarded as relevant to glaucoma progress. Optical coherence tomography （OCT） is a noninvasive image acquisition technology, which can be applied in observing the deep structure of eyeball. Meanwhile, the combination of enhanced depth imaging-OCT （EDI-OCT） and image procesing software makes it possible for us to observe the fundus of glaucoma and quantify the laminar relevant structure,which plays an important role in the diagnosis and treatment of the disease.