针刀治疗椎动脉型颈椎病的Meta分析

The Meta-analysis of the Needle Knife Treatment of Cervical Spondylosis of Artery Type

目的探讨针刀治疗椎动脉型颈椎病(CSA)的疗效并进行Meta分析。方法检索Pub Med、中国生物医学文献数据库、中国期刊全文数据库、中文科技期刊全文数据库自收录以来至2014年11月已发表或未发表的针刀治疗CSA的相关临床随机对照试验,采用Cochrane协作网提供的Review Manager 5.2软件对所纳入的高质量随机对照试验进行Meta分析。文献的每次筛选与所进行的文献Jadad评分均由2位研究者独立进行,意见不统一时通过协商解决或征求第三方意见。结果有6篇较高质量的随机对照文献纳入Meta分析,总纳入病例数为409例。Meta分析结果显示,应用针刀干预CSA的总治愈率与针刺或西药(氟桂利嗪)的疗效比较差异有统计学意义(OR=1.78,95%CI 1.15~2.75;I^2=48%,P=0.05)。结论针刀治疗CSA的治愈率与针灸或西药(氟桂利嗪)的治愈率相比有明显的优越性。

Objective To compare the effect of needle knife in treatment of the cervical spondylosis of artery type（ CSA ）. Methods The database of PubMed, Chinese biomedical literature database, Chinese journal full-text database and Chinese science and technology journal full-text database were searched for papers of clinical randomized controlled trials of needle knife for the treatment of CSA published/unpublished before November 2014 ,and Review Manager 5.2 software provided by Cochrane Collaboration Network was used for the meta-analysis of the included trims. Jadad score of each screened paper was carried out by two researchers independently, and disagreement was solved through discussion or consulting a third opinion. Results Eventually six articles including 409 cases were included in the meta-analysis. Meta-analysis results indicated the total cure rate of needle knife intervention of CSA compared with acupuncture and west- ern medicine（flunarizine） treatment was statistically significantly different（ OR = 1.78,95% CI 1.15-2. 75 ; 12 =48% ,P =0.05）. Conclusion Compared with acupuncture and western medicine（tlunarizine） ,the cure rate of needle knife is superior for the treatment of CSA.