i-scan内镜在上消化道癌筛查中的应用

Endoscopy with i-scan for upper gastrointestinal cancer screening

目的探讨i-scan内镜在上消化道癌筛查的应用。方法将进行上消化道癌筛查的人群随机分为白光模式组和i-scan模式组,各3 000例,比较两组镜下检出病例检出率、随访病例检出率、早诊率及敏感度、特异度。结果i-scan模式组检出病例检出率、随访病例检出率与白光模式组相比有统计学差异（χ~2=4.41,P〈0.05;χ~2=4.81,P〈0.05）。i-scan模式组检出病例、随访病例的敏感度（82.35%、79.14%）均高于白光模式组（78.13%、65.54%）;i-scan模式组早诊率（12.00%）高于白光模式组（6.67%）,两组早诊率相比有统计学差异（P〈0.05,χ~2=4.61）。结论 i-scan技术提高了上消化道癌及癌前病变的检出率,在上消化道早癌筛查中有很大的应用价值。

Objective To explore the application of endoscopy with i-scan in the screening of upper gastrointestinal cancer. Methods Subjects who were to undergo upper gastrointestinal cancer screening in our hospital were randomly divided into two groups,endoscopy with i-scan group（ n = 3 000）,and white light endoscopy group（ n = 3 000）.Detection rate,early detection rate,sensitivity and specificity of the two groups were compared. Results Compared with white light endoscopy group,the endoscopy with i-scan group show ed better detection rate（ P〈 0. 05）. The sensitivity,specificity and early detection rate of endoscopy with i-scan group were 82. 35%,79. 14%,and 12%,while those of the white light endoscopy group were 78. 13%,65. 54% and 6. 67%,with statistically significant differences between the two groups（ P 〈0. 05）. Conclusion Endoscopy with i-scan can improve the detection rate of upper gastrointestinal cancer and precancerous lesions. It is a valuable technique for upper gastrointestinal cancer screening.