黑升麻提取物对去势大鼠体温的影响

目的:观察黑升麻提取物对去势大鼠体温的影响。方法:雌性Sprague-Dawley(SD)大鼠30只,随机分为假手术(Sham)组、去势(OVX)组及去势后黑升麻提取物治疗(OVX+BC)组,每组10只。使用相应药物分别治疗并监测体温8周。结果:1与Sham组比较,OVX组及OVX+BC组大鼠的平均体温明显升高(P<0.05);2与OVX组比较,OVX+BC组大鼠的平均体温明显减低(P<0.05)。结论:大鼠去势后会出现体温升高。黑升麻提取物可以使去卵巢大鼠体温下降,达到缓解围绝经期潮热症状的目的。

objective: to observe the black cohosh extract the influence of the temperature of castrated rats. Methods: the female Sprague wrote- Dawley(SD)rats 30, were randomly divided into control group(Sham), castration group(OVX) and castrated and black cohosh extract treatment group(OVX + BC), 10 in each group. Using the corresponding drug treatment and monitoring temperature 8 weeks respectively. Results:(1) compared with the Sham group, the OVX group and the OVX + BC the average temperature of rats increased significantly(P < 0.05);(2) compared with OVX group, the OVX + BC group significantly reduced the average temperature of rats(P < 0.05). Conclusion: body temperature will be shown after the castrated rats. Black cohosh extract can make the temperature drops to ovarian rats, achieve the goal of relieve menopausal hot flashes around.