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调节性T细胞在肿瘤免疫和肿瘤免疫治疗中的作用

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摘要 肿瘤是当前世界上常见的慢性渐进性疾病,生长速度快,转移性高,治愈性低且易复发,给临床治疗造成了极大的困难。当前的治疗手段有手术切术、化疗等方法,但是仍然没有从根本上提高肿瘤的治愈率。肿瘤局部存在着多种类型的免疫抑制性细胞,其中T细胞通过多种机制抑制免疫细胞的功能,使肿瘤免疫得以逃避。包括分泌颗粒酶和穿孔酶杀伤效应细胞、扰乱效应细胞的功能、分泌抑制性细胞因子等手段。对于肿瘤治疗的突破需要我们通过多种途径进行,而调节T细胞成为肿瘤治疗的又一突破口。
作者 姜显亭
出处 《生物技术世界》 2016年第1期111-111,共1页 Biotech World
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