天和骨通贴膏治疗膝骨关节炎的临床疗效评价研究

Clinicl Analysis of Tianhe Bone Ache Paste Used to Treat Knee Osteoarthritis

目的:评价天和骨通贴膏治疗膝骨关节炎的临床疗效。方法:将72例膝骨关节炎患者按完全数字随机表法分为天和骨通贴膏组(36例)和复方紫荆消伤膏组(36例),各组分别予相应的巴布膏剂治疗,疗程均为28天,观察临床疗效、主要症状及MRI变化情况。结果:治疗后两组临床评分改善程度天和骨通贴膏组较复方紫荆消伤巴布膏组为高,但没有显著性差异(P>0.05);治疗组与对照组治疗后以及与治疗前在软骨水肿发生率、受累关节面、水肿平均直径(mm)方面的差异具有明显的统计学意义(P<0.05)。结论:天和骨通贴膏与复方紫荆消伤巴布膏治疗膝骨关节炎均有较好的临床疗效,其中天和骨通贴膏在降低软骨水肿发生率、减少受累关节面及水肿平均直径(mm)方面优于对照组。

Objective: To observe the clinical efficacy of “TIANHE Bone Ache Paste” in the treatment of Knee Osteoporosis. Methods:72 subjects were randomized into two groups:treatment group in which 36 cases were treated with “TIANHE Bone Ache Paste”,another were treated with “Compound Redbud Cataplasm”. Both of them were treated with a course of 28 days.The clinical efficacy and main symptoms as pain, tenderness, dysfunction and the change of MRI were observed.Results:After treatment, the degree of improvement in clinical scores group “TIANHE Bone Ache Paste” was better than group “Compound Redbud Cataplasm”, but there was no significant difference(P>0.05); after treatment, the difference between group “TIANHE Bone Ache Paste” and group “Compound Redbud Cataplasm” in aspects of the incidence of cartilage edema, the involvement of articular surface and the average diameter of edema(mm)were statistically significant(P<0.05).Conclusion:Both of them could get better clinical efficacy, in which group “TIANHE Bone Ache Paste” in reducing the incidence of cartilage edema, the swelling of the affected joint surface and the average diameter(mm)were better.