阿奇霉素联合炎琥宁治疗儿童肺炎支原体肺炎的疗效分析

Clinical analysis of azithromycin combined with andrographolide in treating children mycoplasmal pneumonia

目的分析阿奇霉素联合炎琥宁治疗儿童肺炎支原体肺炎的疗效。方法抽选2013年4月~2014年6月我院收治的肺炎支原体肺炎患儿162例,随机法分为观察组（n=81）和对照组（n=81）,对照组患儿给予阿奇霉素治疗,观察组在此基础上加用炎琥宁治疗,用药前先用5%葡萄糖注射液进行冲管。对比两组患儿治疗疗效及临床症状积分改善情况。结果观察组总有效率95.8%,显著高于对照组80.3%,差异有统计学意义（P〈0.05）。观察组临床症状积分治疗1周及治疗后下降至（8.1±4.7）分、（3.2±1.96）分,显著低于对照组（14.2±3.0）分、（8.3±2.4）分,两组相比差异有统计学意义（P〈0.05）。结论阿奇霉素联合炎琥宁治疗儿童肺炎支原体肺炎疗效显著增强,能迅速缓解患儿干咳、咽痛、头痛、发热等临床症状。

Objective： To investigate the clinical effect of azithromycin combined with andrographolide in treating children mycoplasmal pneumonia. Methods- 162 cases with mycoplasmal pneumonia in our hospital from April 2013 to June 2014 were selected. They were divided into observation group （n=81） and control group （n=81）. Control group was given azithromycin treatment and observation group was given andrographohde based on control group. The first 3 days, 5% glucose injection was used to wash pipe. Compared the clinical effect and clinical symptoms integral improvement of the two groups. Results： Total effective rate of observation group （95.8%） was obviously higher than control group （80.3%）, the difference was statistically significant （P〈0.05）. Clinical symptoms integral of observation group dropped to （8.1 ± 4.7 ） score, （ 3.2 ± 1.96 ） score after one week and after treatment, obviously lower than control group （ 14.2 ± 3.0 ） score, （ 8.3 ± 2.4 ） score, the difference was statistically significant （P〈0.05）. Conclusion： Azithromycin combined with andrographolide in treating children mycoplasmal pneumonia has significant effect, it can quickly ease the clinical symptoms like dry cough, sore throat, headache, fever and so on.