4Philipp T, Smith TR, Glazer R, et al. Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension[J]. Clin Ther, 2007, 29(4) :563-580.
5Allemann Y, Fraile B, Lambert M, et al. Efficacy of the combi nation of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy= the Exforge in failure after single therapy (EX-FAST) study[J]. J Clin Hypertens (Greenwich) ,2008,10(3) : 185-194.
6Destro M, Luckow A, Samson M, et al. Efficacy and safety of amlodipine/valsartan compared with amlodipine monotherapy in patients with stage 2 hypertension= a randomized, double blind, multicenter study: the EX-EFFeCTS study[J]. J Am Soc Hyper- tens,2008,2(4) :294 302.
8Hu D, Liu L, Li W. Efficacy and safety of valsartan/amlodipine single-pill combination in 11 422 Chinese patients with hyperten sion: an observational study[J]. Adv Ther,2014,31(7) :762- 775.
9Turnbull F, blood pressure lowering treatment trialists' collabora- tion. Effects of different blood-pressur-lowering regimens on ma jot cardiovascular events: results of prospectively-designed over views of randomised trials[J]. Lancet, 2003,362 (9395): 1527- 1535.
