百会透刺前顶对1、2级原发性高血压动态血压的影响

Effect of puncturing from Bǎihuì(百会GV20 ) to Qiándǐng(前顶GV21 ) with penetrating method on ambulatory blood pressure in grade 1 and 2 primary hypertension

目的通过24 h动态血压监测观察百会透刺前顶对1、2级原发性高血压动态血压的影响,评价其有效性及安全性。方法选择符合1、2级原发性高血压诊断标准的患者120例,随机分为对照组和治疗组各60例,剔除脱落病例21例,最终治疗组纳入49例,对照组纳入50例。对照组予健康教育生活方式干预;治疗组在此基础上,予百会透刺前顶穴治疗,2组均于治疗前及治疗4、12周时监测24 h动态血压,计算24 h平均收缩压、平均舒张压、平均脉压差、脉压指数、平滑指数,并进行降压疗效比较。结果第4、12周,对照组和治疗组均能降低24 h平均收缩压、平均舒张压、脉压指数,与治疗前比较差异有统计学意义(P<0.01);对照组12周时各指标与4周时比较差异均无统计学意义(P>0.05);治疗组12周时与4周时比较差异均有统计学意义(P<0.05);4周、12周时各指标组间比较,治疗组均优于对照组(P<0.05)。2组降压总有效率比较,第4、12周差异均有统计学意义(P<0.01)。结论百会透刺前顶治疗原发型高血压1、2级能显著降低24 h平均收缩压、平均舒张压、平均脉压差、脉压指数,可持续、平稳、有效地降低24 h血压,降压疗效显著优于仅予健康教育生活方式干预。

ABSTRACT Objective To observe the effect of puncturing from Bǎihuì（百会GV20）to Qiándǐng（前顶GV21）with penetrating me!hod on ambtdatory blood presauw in grade 1 and 2 primary hypertension by 24-hour ambulatory blood pressure monitoring, and evaluate its effectiveness and safety. Methods !20 patients with primary hypertension of 1-2 level were randomized into the control group and treatment group of 60 eacK After 21 dropping cases were excluded, 49 were finally included in the treatment group and 50 in the control group. The control group were given health education and lifestyle intervention, the treatment group were given acupuncture from Bǎihuì（百会GV20）to Qiándǐng（前顶GV21） with penetrating method plus health education and lifestyle intervention. Before treatment and at week 4 and 12 after treatment, two groups were monitored by 24-h ambulatory blood pressure, 24-h average systolic and diastolic blood pressure, mean pulse pressure difference, pulse pressure index, smoothness index calculated, and the antihypertensive efficacy compared. Results To compare with that before the treatment, the 24-h average systolic and diastolic blood pressure, mean pulse pressure difference, pulse pressure index could be reduced at week 4 and 12 in the control group and the treatment group, and the difference had statistical significance （ P 〈 0.01 ）, The data in the control group at week 12 and week 4 showed no significant difference （ P 〉 0. 0,5 ） ; to compare the data between week 4 and week 12 in the treatment group, the difference were statistically significant （P 〈0,. 05）. To compare the data between the two groups at week 4 and week 12, the treatment group was hotter than the control group （ P 〈 0. 05 ）. To compare the total effectiveness of two arouos, the difference at week 4 and week 12 was statically significant （P 〈0. Ol ）. Conclusion Acupuncture from Bǎihuì（百会GV20）to Qiándǐng（前顶GV21） with penetrating method can signifit：antly reduce 24-h average systolic and diastolic bloom pressure, mean pulse pressure difference, pulse pressure index in grade 1 and 2 primary hypertension, and reduce 24-h blood pressure in a sustainable, stable and effective way. The antihypertensive effect was obviously better than health education and lifestyle intervention.