黑龙江地区女性乳腺密度与乳腺癌的风险因素相关性研究

Correlation between breast density and breast cancer risk factors in Heilongjiang area

目的探讨黑龙江地区乳腺癌与其乳腺密度是否存在相关性。方法收集2010年6月至2010年11月哈尔滨医科大学附属第一医院就诊的487例黑龙江地区女性的乳腺钼靶X线检查资料及流行病学资料,其中105例为乳腺癌,382例为健康对照组,以美国放射医师学会推荐的乳腺影像报告和数据系统(breast imaging reporting and data system,BI-RADS)作为评估乳腺密度的标准,以乳腺密度百分比分析不同等级乳腺摄影密度和乳腺癌危险因素的关系。结果乳腺癌组与健康对照组乳腺密度有统计学差异。绝经状态未对乳腺密度产生影响;乳腺密度与初潮年龄、哺乳史相关。结论乳腺X线摄影密度与乳腺癌危险因素均相关联。

Objective To explore the correlation between breast cancer and breast density in Heilongjiang region. Methods X-ray data and epidemiologieal data of 487 women from June 2010 to November 2010 in the First Affiliated Hospital of Harbin Medical University were col- lected, including 105 cases of breast cancer and 382 cases of healthy controls（ breast benign disease）. Breast imaging reporting and data system recommended by americaradiology doctors was the standard for evaluation of breast density, breast density percentage was used to analyze the relationship between different levels of mammary gland photography density and breast cane- er risk factors. Results Based on 487 cases of mammary X-ray data, breast density was statis- tically different between breast cancer groups and healthy controls in Heilongjiang area, the oc- currence of breast cancer was associated with a high breast density, menopausal status did not affect breast density; breast density was associated with menarche age and history of lactation. Conclusion Breast X-ray photography density is associated with breast cancer risk factors.