金昌队列人群代谢综合征发病状况研究

Study on Incidence of Metabolic syndrome in Jinchang Cohort

目的了解金昌队列人群代谢综合征不同组分及不同特征人群发病情况,为降低代谢综合征发病率提供基础性数据。方法选取金昌队列随访人群28 688例,以其中基线调查未患有代谢综合征者24 641例为研究对象,分析基线未患有代谢综合征者2年后发病及相关情况。应用卡方检验进行代谢综合征不同组分之间发病率差异显著性检验。结果金昌队列人群代谢综合征2年累积发病率为7.61%,标化发病率为6.99%。男性标化发病率高于女性,标化发病率分别为8.68%和4.47%。不同组分高血压发病率最高,高血糖发病率最低。内勤服务人员、教育程度小学及以下、有吸烟史、有饮酒史、高盐和高油脂饮食者发病率高于其他特征人群。结论金昌队列人群代谢综合征发病率随年龄增长呈明显上升趋势。60岁以上人群是该人群代谢综合征发病高危人群,应尽早予以干预。同时,高血压和血脂代谢异常人群是该人群代谢综合征防治的重点。

Objective To study the incidence of metabolic syndrome among different individual and people with different characteristics in the Jinchang Cohort and provide basic evidence for reducing the incidence of the metabolic syndrome. Methods 24 641 subjects without a history of metabolic syndrome at baseline data collection were selected from the 28 688 follow-up subjects among which the incidence of metabolic syndrome after two years and the relevant circumstances were analyzed. The difference in incidence between different subgroups was evaluated using Chi-square test. Results The 2 year cumulative incidence of metabolic syndrome in the Jinchang Cohort was 7.61%, and the standardized incidence was 6.99%. The standardized incidence was higher in males than in females （8.68% vs 4.47%）. The incidence of hypertension was the highest in different groups, and the incidence of hyperglycemia was the lowest. Indoor service staff and people with education level of primary school or below, a history of smoking or drinking, or high salt or oil consumption diet had a higher incidence of metabolic syndrome compared to others subgroups. Conclusion The incidence of metabolic syndrome in Jinchang cohort increased with age. The population with over 60 years of age have elevated risk for metabolic syndrome and should begin early intervention. Of the metabolic syndrome components, individuals with hypertension and abnormal lipid metabolism are the focus of prevention and treatment of metabolic syndrome.