中央型非小细胞肺癌手术治疗160例临床分析

An analysis of 160 cases with central non-small cell lung cancer underwent surgeries

目的总结手术治疗中央型非小细胞肺癌（NSCLC）的临床效果。方法回顾性分析160例中央型NSCLC患者的临床资料。术前均经纤维支气管镜检查,病理确诊。其中,肿瘤位于主支气管11例,肿瘤侵及叶支气管开口35例。结果常规肺叶切除术100例,支气管袖状肺叶切除29例,全肺切除31例。术后未发生支气管胸膜瘘的并发症。149例获得随访8~72个月;手术切除病例的1年生存率86.8%,3年生存率45.8%,5年生存率24.5%。结论手术是治疗中央型NSCLC的主要手段。手术方式应依据支气管受肿瘤侵及的程度和患者肺功能情况选择常规肺叶切除、袖状肺叶切除或全肺切除术。

Objective To summarize the clinical outcomes of the patients with central non-small cell lung cancer（NSCLC）underwent surgeries.Methods The data of 160 cases with central NSCLC were retrospectively analyzed.Central NSCLC of all cases was diagnosed pathologically after fibrobrochoscopy.The tumors located at main bronchus in 11 cases and invaded the opening of the bronchus in 35 cases.Results Conventional lobectomy was performed in 100 cases,bronchial sleeve resection was performed in 29 cases,and pneumonectomy was carried out in 31 cases.Bronchopleural fistula did not occurr after operation.A total of 149 cases was followed up for 8 to 72 months,which showed that one-,three-,and five-year survival rates were 86.8%,45.8%,and 24.5%,respectively.Conclusion Surgery is the main method in the treatment of central NSCLC.Surgical techniques of conventional lobectomy,bronchial sleeve resection and pneumonectomy are selected according to the invasive degrees of the bronchus by tumor and the lung function of the patients.