诺和灵30R治疗妊娠期糖尿病的疗效分析

Efficacy of Novolin 30R in the Treatment of Gestational Diabetes Mellitus

目的:探讨诺和灵30R治疗妊娠期糖尿病的疗效。方法:根据治疗方案将2012年5月-2015年4月江西省妇幼保健院收治的132例妊娠期糖尿病患者分为观察组72例与对照组60例,观察组采用诺和灵30R治疗,对照组采用诺和灵R联合诺和灵N治疗。结果:治疗前,两组的空腹血糖、餐后2 h血糖、糖化血清蛋白、糖化血红蛋白比较差异均无统计学意义(P>0.05)。治疗后,两组的空腹血糖、餐后2 h血糖、糖化血清蛋白、糖化血红蛋白均显著下降,治疗前后比较差异均有统计学意义(P<0.05),但两组间比较差异均无统计学意义(P>0.05)。两组的血糖达标率、低血糖发生率比较差异均无统计学意义(P>0.05)。观察组未按时注射胰岛素发生率显著低于对照组,两组比较差异有统计学意义(P<0.05)。结论:诺和灵30R治疗妊娠期糖尿病的疗效确切,且依从性良好,是治疗妊娠期糖尿病的理想选择。

Objective：To explore the efficacy of Novolin 30 R in the treatment of gestational diabetes mellitus.Method：132 cases of gestational diabetes mellitus who were admitted into the Jiangxi Maternal and Child Health Hospital were selected from May 2012 to April 2015,they were divided into the observation group of 72 cases and control group of 60 cases according to their therapeutic regimen.The observation group was given Novolin 30 R, while the control group was given Novolin R and Novolin N.Result：Before treatment,the differences of fasting glucose, 2-hour postprandial blood glucose, glycated albumin and glycosylated hemoglobin between two groups were no statistically significant（P〈0.05）.After treatment, the fasting glucose,2-hour postprandial blood glucose, glycated albumin and glycosylated hemoglobin of two groups decreased significantly, compared with those before treatment,the differences were statistically significant（P〈0.05）, but there were not significant differences of those in two groups（P〉0.05）.The differences of blood glucose standard-reaching rate and incidence of hypoglycemia between two groups were not statistically significant（P〉0.05）.The incidence of inject insulin unpunctually in observation group was significantly lower than that in control group, the difference was statistically significant（P〈0.05）.Conclusion：The Novolin 30 R in the treatment of gestational diabetes mellitus shows good efficacy and compliance, which is an ideal choice for gestational diabetes mellitus.