93例贫血患者外周血涂片红细胞形态学分析

Analysis on peripheral blood smear red blood cell morphology in 93 patients of anemia

目的探讨贫血患者外周血红细胞的形态学特征。方法选择93例贫血患者的外周血涂片在全自动阅片仪上进行红细胞形态学检查,对于异形性红细胞采取人工镜检。结果 93例贫血患者经DM-96全自动血细胞形态分析系统分析,红细胞大小不均占77.4%,其中48.4%以小红细胞为主,异形性红细胞占55.9%,嗜多色性红细胞人工镜检与仪器自动阅片检出率差异较大,低色素性红细胞占11.8%。异形性红细胞形态中检出率居前三位的是椭圆形红细胞、红细胞碎片及红细胞缗钱状排列。结论外周血红细胞形态学分析在红细胞疾病,尤其是贫血的诊断、预后、治疗中具有重要的意义,为实验室报告的可靠性提供了形态学上的重要依据。

Objective To investigate the morphological characteristics of peripheral blood red blood cell（RBC） in the patients with anemia. Methods The peripheral blood smears were selected from 93 cases of anemia and performed the morphological examination by the automatic reading instrument,the heteromorphic red blood cells were examined by the manual microscopy. Results Amgng 93 patients of anemia analyzed by the DM-96 automatic blood cell morphological analytical system,anisocytosis accounted for 77.4%, in which 48.4% were mainly microcytic, heteromorphic RBC accounted for 55.9%, the detection rate of polychromato-phil RBC had large difference between the manual microscopy and the instrument automatic reading,the hypochromic RBC accoun- ted for 11.8%. The top three places of detection rates in heteromorphic RBC were elliptocyte,RBC fragment and RBC rouleaux ar- rangement. Conclusion Peripheral blood erythrocyte morphology analysis has an important significance in the RBC diseases,especially in the diagnosis, prognosis and treatment of anemia, which provides the important basis of morphology for the reliability of laboratory report.