养血清脑颗粒联合氟桂利嗪胶囊对慢性脑供血不足患者认知功能障碍和睡眠障碍的影响

Effect of Yangxue qingnao particles combined with flunarizine hydrochloride capsules in improving the function of per-ception and the quality of sleeping in chronic cerebral circulation insufficiency

目的：观察养血清脑颗粒联合氟桂利嗪胶囊（西比灵）对慢性脑供血不足患者认知功能障碍及睡眠障碍的影响。方法将90例慢性脑供血不足患者随机分为两组（实验组和对照组），对照组顿服盐酸氟桂利嗪胶囊每晚一次，一次10 mg ；治疗组给予养血清脑颗粒每日3次，每次1袋，并顿服盐酸氟桂利嗪胶囊每晚一次，每次10 mg ；两组均连续用药1个月，观察疗效。评价指标包括两组患者临床总有效率比较、认知功能得分比较和失眠缓解率的比较。结果治疗组临床症状总有效率为75．6％，明显优于对照组的58．5％（P ＜0．05）。认知功能与失眠缓解率在两组之间也具有统计学意义。结论养血清脑颗粒联合氟桂利嗪胶囊能够改善慢性脑供血不足患者认知功能障碍及睡眠障碍。

Objective To observe the effect of Yangxue qingnao particles combined with flunarizine hydrochlo‐ride capsules in improving the function of perception and the quality of sleeping in chronic cerebral circulation insuffi‐ciency .Methods 90 patients with chronic cerebral circulation insufficiency were randomly divided into the treatment group（48cases） and control group （42 cases） ,study group were given flunarizine hydrochloride capsules and Yangxue qingnao particles ,control group were given only flunarizine hydrochloride Capsules .Both of them were treated for one month .To observe curative effect after one month treatment and the score of the function of perception .Results The total clinical effective rate was 75 .6% of treatment group and 58 .5% of control group .The difference was between＆amp;nbsp;two groups was statistically significant（P〈 0 .05） .The function of perception and the quality of sleeping are different between the two groups .Conclusion Effect of Yangxue qingnao particles combined with flunarizine hydrochloride capsules in improving the function of perception and the quality of sleeping in chronic cerebral circulation in sufficien‐cy is better than flunarizine hydrochloride capsules used alone .