宁夏回族地区疑难交叉配血原因分析

Analysis of difficult blood cross matching in NingXia Hui Autonomous Region

目的：通过对58例疑难配血病例资料进行分析，了解宁夏回族地区临床产生疑难配血原因，探索解决疑难配血的对策。方法收集本地区2013年1月至2014年12月医疗机构送检的58例疑难交叉配血病例，进行回顾性分析，总结交叉配血不合的原因，并提出解决对策。结果58例疑难配血病例中，以不规则抗体最为常见，占82．7％，其中同种抗体占55．2％，自身抗体占27．6％。高效价冷抗体占6．9％，ABO 亚型占10．3％。结论引起交叉配血不合的原因是多方面的，其中不规则抗体是导致本地区临床疑难配血的最主要原因，不规则抗体的特异性及分布存在地区多样性。分析配血不合的原因，采用合适的试验技术排除影响因素，保证交叉配血的成功及输血安全。

Objective To find out the clinical difficult blood maching reasons in Ningxia Hui Autonomous Re‐gion by 58 cases difficult blood cross matching of the data analyses ,and explore the strategy for solve the difficult blood cross matching .Methods The cases of difficult blood maching tested by the medical institutions were collected from 2013 .1 to 2014 .1 ,and were analyzed retrospectively .Summarizes the causes of crossmatching incompatibility and puts forward solving countermeasure .Results The irregular antibody is most common ,in 58 cases of difficult blood cross matching ,accounting for 82 .7% ,which accounted for 55 .2% of the alloantibody ,autoantibodies for 27 . 6% ,high titer cold antibody accounted for 6 .9% ,and ABO subtype accounted for 10 .3% .Conclusion Reasons which causes crossmatching incompatibility are in many aspects .Where irregular antibodies are clinically difficult cause blood in the region with the most important reason ,irregular antibodies are present regional diversity for speci‐ficity and distribution .Analysising of the reasons for crossmatching incompatibility ,to ensure the success of the blood cross‐matching and blood transfusion safety ,using appropriate test techniques .