3867例孕妇和新生儿TORCH—IgM检测结果分析

Analysis of the TORCH-IgM test results of 3 867 cases of pregnant women and newborns

目的探讨孕妇和新生儿TORCH（弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒Ⅰ＋Ⅱ型）感染的状况及临床意义，为妇幼保健提供参考依据。方法采用意大利索灵uAISONXL化学发光免疫分析系统检测3867例孕妇和新生儿血清中的TORCH-IgM抗体。结果2042例孕妇中TORCH—IgM阳性为74例，总阳性率为3．62％。其中TOX、RUV、CMV和HSVⅠ＋Ⅱ特异性IgM阳性率分别为0．39％（8／2042）、1．57％（32／2042）、0．78％（16／2042）、0．88%（18／2042）。1825例新生儿中TORCH—IgM阳性为53例，总阳性率为2．9％。其中TOX、RUV、CMV、HSVI＋Ⅱ特异性IgM阳性率分别为0．27％（5／1825）、0．22％（4／1825）、1．97％（36／1825）、0．44％（8／1825）。结论孕妇RUB的感染率最高，新生儿CMV感染率最高，TORCH感染不容忽视，对优生优育有着重要关系，应进行早期及时筛查，最好同时检测TORCH—IgG，对诊断和治疗具有重要意义。

Objective Pregnant women and newborn TORCH（toxoplasma,rubella virus, cytomegalovirus, her pes simplex virus Ⅰ＋Ⅱ） infection status and clinical significance of provide reference basis for maternal and child health. Methods Adopts the Italian Diasorin LIAISON XL chemiluminescence immunoassay system testing, 3 867 cases of pregnant women and newborn TORCH-IgM antibody in the serum. Results 2 042 cases of pregnant women in the TORCH-IgM for 74 cases,total positive rate was 3.62%. The TOX,RUV,CMV and HSV Ⅰ＋Ⅱ specific IgM positive rate was 0. 39%（8/2042） ,1.57%（32/2042） ,0.78%（16/2042） ,0.88% （18/2042）. Of 1825 cases of neonatal TORCH-IgM for 53 cases,total positive rate was 2.9%. The TOX,RUV,CMV and HSV Ⅰ＋Ⅱ specific IgM posi- tive rate was 0. 27%（5/1825）,0. 22% （4/1825） and 1. 97%（36/1825）, 0. 44% （8/1825）. Conclusion Pregnant women RUB the infection rate is highest,the newborn CMV infection rate is highest, the TORCH infection should not be ignored, to have important relations of eugenic and superior nurture, should be timely early screening, the best detection at the same time the TORCH-IgG,is of great importance in the diagnosis and treatment.