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Wnt/β-catenin信号通路在慢性肾脏病血管钙化中作用的研究进展 被引量:2

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摘要 慢性肾脏病(chronic kidney disease,CKD)患者血管钙化(vascular calcification,VC)的发生率高、危害性大,具体发病机制仍未明确。近期研究发现Wnt/β-catenin信号通路参与VC的发生与发展,与慢性肾脏病矿物质和骨异常(chronic kidney disease-mineral and bone disorder,CKD-MBD)的骨-血管轴密切相关,并且在CKD病程中的调节出现异常,本文就Wnt/β-catenin信号通路在慢性肾脏病血管钙化中作用的研究进展做一综述。
作者 邓岱 刘文虎
出处 《医学研究杂志》 2016年第1期170-173,共4页 Journal of Medical Research
基金 国家自然科学基金资助项目(81300607) 北京市科技计划项目(D131100004713001)
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