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人乳头状瘤病毒E6/E7 mRNA研究进展 被引量：11

Research progression of human papillomavirus E6/E7 mRNA
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摘要 高危型人类乳头状瘤病毒的持续感染是宫颈癌发生的首要原因,E6、E7致癌基因过度表达是促使宫颈病变进展的关键因素。本文就E6、E7致癌机制及其与宫颈病变程度的相关性、人乳头状瘤病毒E6/E7mRNA检测方法及其临床应用的研究进展作一综述。 Persistent infection of high-risk human papillomavirus （HPV） is the main cause of cervical cancer, and the overexpressions of oncogenes E6 and E7 are the key factors of the progression of cervical lesions. This paper reviews the relationship of the carcinogenic mechanism of E6 and E7 with the degree of cervical lesions, the testing technique of HPV E6/E7 mRNA and its clinical application.
作者 吕秀芳 孔令非
机构地区 郑州大学人民医院河南省人民医院病理科
出处 《中华实用诊断与治疗杂志》 2016年第2期111-113,共3页 Journal of Chinese Practical Diagnosis and Therapy
基金 河南省科技攻关计划项目(142102310395)
关键词 宫颈癌 人类乳头状瘤病毒 E6/E7 MRNA Cervical cancer human papillomavirus E6/E7 mRNA
分类号 R737.33 [医药卫生—肿瘤]
  • 相关文献

参考文献19

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二级参考文献22

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共引文献16

同被引文献95

  • 1刘宇,罗治彬,王彝,邓悦.212例口腔癌患者的流行病学危险因素分析[J].实用癌症杂志,2014,29(2):160-162. 被引量：22
  • 2鲍彦平,乔友林.子宫颈癌简单快速筛查方法研究进展[J].中国医刊,2007,42(8):19-22. 被引量：6
  • 3陈燕青,王家东.头颈部多原发癌——附28例病例分析[J].现代肿瘤医学,2007,15(12):1758-1761. 被引量：3
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引证文献11

二级引证文献88

中华实用诊断与治疗杂志
2016年 第2期

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