病理大切片技术在胃癌大部切除术后应用价值及优势探讨

The value and advantages of pathological large section in gastric cancer after subtotal gastrectomy

目的探讨病理大切片技术在胃癌患者胃大部切除术后标本的应用价值,并与常规切片制片技术进行比较。方法收集2012年5月-2014年12月广西中医药大学第一附属医院胃癌患者胃大部切除术后标本,比较病理大切片与常规病理切片的阳性率,并比较癌旁组织切片和切口边界癌组织阳性检出率。结果病理大切片技术癌旁组织切片、切口边界切片阳性率高于常规制片（χ~2=6.13,P〈0.05;χ~2=8.93,P〈0.05）。结论病理大切片技术在病理诊断、形态学研究方面有着明显的优势,对于一些体积微小、形态不明显的癌组织阳性检出率高,更适合作为癌症诊断的金标准。

Objective To investigate the application value of pathological large section technique in patients with gastric cancer after subtotal gastrectomy, and compare with the traditional section technique. Methods Seventy-eight cases of gastric cancer from 2012 to 2014 were selected in this study, the positive rate was compared between pathologi- cal large section and traditional section. Results The positive rate in pathological large section group was significantly higher than that in traditional section group, both in paracancer （χ2 = 6. 13, P 〈 0.05） and HCC tissue sections （χ2 = 8.93, P 〈 0.05）. Conclusion Pathological large section technology has a significantly advantage in pathological diag- nosis and morphological study. It is more suitable as a cancer diagnostic standard.