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miRNAs调控肝星状细胞生物学活性机制研究进展 被引量:5

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摘要 肝星状细胞(HSCs)是肝纤维化形成的最主要细胞,其生物学活性已成为防治肝纤维化重要的治疗靶点。但是,迄今尚无十分有效的逆转肝纤维化的治疗手段。微小RNA(miRNA)是转录后水平的细胞调控因子,多项研究发现miRNA通过参与HSC的活化、增殖和凋亡等生物学活性的调控,在肝纤维化的发生、发展过程中具有重要作用,有望成为肝纤维基因治疗的新靶点。
出处 《山东医药》 CAS 北大核心 2016年第2期101-103,共3页 Shandong Medical Journal
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