急性1,2-二氯乙烷中毒临床研究进展

Clinical research progress on acute 1,2-dichloroethane poisoning

1,2-二氯乙烷是常见的高挥发性有机溶剂,广泛用于玩具、制鞋等行业。近年严重的急性中毒事件频发,其发病特点、临床表现、影像学特点等与过往报道不尽相同。本文通过收集国内外近10年相关文献报道,从发病情况、中毒机制、现场流行病学特征、中毒的临床表现、脑部影像学表现、鉴别与诊断、治疗与预后等方面,总结了有关其中毒的研究进展。

1,2-dichloroethane, one of the high volatile organic solvents, is widely used in toy and footwear manufactures. Severe acute 1,2-dichloroethane poisoning incidents have been found in high frequency in recent years and the victims showed some new features different from previous reports, such as incident type, clinical manifestation and image characteristics. Therefore, we reviewed the case reports and research papers published in the last 10 years, both in Chinese and English,to summarize the research progress in the morbidity,poisoning mechanisms,epidemiology features, clinical manifestations, image characteristics of the brain, identification and diagnosis, treatment and prognosis, and so on.