期刊文献+

蛋白激酶C-δ特异性脱氧核酶对HepG2细胞生长的影响

下载PDF
导出
摘要 蛋白激酶C(PKC)存在于细胞浆内,是一类由钙激活的磷脂依赖性丝氨酸/苏氨酸蛋白激酶,与神经传导、肿瘤生长及细胞生长、分化和凋亡等生理病理过程密切相关。依据对二酰基甘油(DAG)和Ca2+的依赖不同,PKC可以分为传统型(cPKC)、新型PKC(nPKC)和非典型PKC(aPKC)[1-3]三类。
作者 魏卓 罗速
出处 《中国实验诊断学》 2016年第1期28-31,共4页 Chinese Journal of Laboratory Diagnosis
基金 吉林省卫生计生青年科研课题(2014Q009)
  • 相关文献

参考文献20

  • 1Pearson RB, Kemp BE. Protein kinase phosphorylafion site se quenees andconsensus speeificily motifs; tabulations[J]. Methods Enzymol 1991 ,200:62.
  • 2Newton AC. Protein kinase G, structure, function and regulation [J]. Biol Chem, 1995,270 : 28495.
  • 3S. Stabel, P. J. Parker, Protein kinase C, Pharmacol[J]. Ther. 51 (1991) 71.
  • 4M. Castagna, Y. Takai, K. Kaibichi, K. Sano, U. Kikkawa, Y. Nishizuka, Direct activation of calcium-activated, phospholipid-de- pendent protein kinase by tumor-promoting phorbol esters[J]. Bi- ol. Chem. 257 (1982) 7847.
  • 5W. C. Faquin,T. J. Schneider,M. A. Goldberg,Modulators of pro- tein kinase C inhibit hypoxia-induced erythropoietin production, Exp[J]. Hematol. 21 (1993) 420.
  • 6Reifel-Miller AE, Conarty DM, Valasek KM, Iversen PW, Burns DJ,Birch KA. Protein kinase C isozymes differentially regulate promoters containing PEA-3/12-O- tetradecanoyl-β-acetate re- sponse element motifs[J]. Biol Chem, 1996,271 : 21668.
  • 7Das KC, White CW. Activation of NF-κB by antineoptastic a- gents. Role of protein kinase C[J]. Biol Chem 1997;272:14914.
  • 8Catley MC,Cambridge LM, Nasuhara Y, Ito K, Chivers JE, Beat- on A,et al. Inhibitors of protein kinase C (PKC) prevent activa- ted transcription. Role of events downstream of NF-κB DNA binding[J]. Biol Chem 2004 ; 279 : 18457.
  • 9Soh JW, Weinstein IB. Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes[J]. Biol Chem 2003 ; 278 : 34709.
  • 10Khachigian LM. Catalytic DNAs as potential therapeutic agents and sequence specific molecular tools to dissect biological func- tion[J]. Clin Invest, 2000,106 : 1189.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部