期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

血友病性骨质疏松的研究进展 被引量：5

原文传递
导出
摘要 血友病是临床上最常见的遗传性出血性疾病,临床主要表现为关节、肌肉和深部组织自发性或轻微外伤后出血难止,若不及时治疗可导致关节畸形和假肿瘤等,严重者可危及生命。男性中发病率约10~20/10万,而女性血友病患者极其罕见,因其关节/肌肉反复出血,大部分患者最终出现关节畸形、肌肉萎缩等并发症,同时,因自发性出血,患者活动减少等原因，部分患者出现骨质疏松。
作者 郝晓阳 闫振宇
机构地区 华北理工大学附属医院血液科
出处 《中国煤炭工业医学杂志》 2016年第1期167-170,共4页 Chinese Journal of Coal Industry Medicine
基金 河北省省级重大医学科研课题(zd2013088)
关键词 血友病 骨质疏松 发病机制 危险因素
分类号 R554.1 [医药卫生—血液循环系统疾病]
  • 相关文献

参考文献28

  • 1汤园园,闫振宇,刘颖,唐秀娟.血友病A腹腔出血合并阴囊、阴茎血肿1例的护理[J].中国煤炭工业医学杂志,2012,15(8):1275-1276. 被引量：2
  • 2Naderi A,Nikvarz M,Arasteh M,et al.Osteoporosis/osteopenia and hemophilic arthropathy in severe hemophilic patients[J].Arch Iran Med,2012,15(2):82-84.
  • 3Barnes C,Wong P,Egan B,et al.Reduced bone density among children with severe hemophilia[J].Pediatrics,2004,114(2):177-181.
  • 4Iorio A,Fabbriciani G,Marcucci M,et al.Bone mineraldensity in haemophilia patients.A meta-analysis[J].Thromb Haemost,2010,103(3):596-603.
  • 5张永光,闫凤民,张拥军,王志强.Osterix和脂联素与骨代谢的关系[J].中国煤炭工业医学杂志,2011,14(5):779-782. 被引量：2
  • 6Katsarou O,Terpos E,Chatzismalis P,et al.Increased bone resorption is implicated in thepatho genesis of bone loss in hemophiliacs.correlations with hemophilic arthropathy and HIV infection[J].Ann Hematol,2010,89(1):67-74.
  • 7Anagnostis P,Vakalopoulou S,Vyzantiadis TA,et al.The clinical utility of bone turnover markers in the evaluation of bone disease in patients with haemophilia Aand B[J].Haemophilia,2014,20(2):268-275.
  • 8Ranta S,Viljakainen H,Mkipernaa A,et al.Hypercalciuria in children with haemophilia suggests primary skeletal pathology[J].Br J Haematol,2011,153(3):364-371.
  • 9Gurevitch O,Slavin S.The hematological etiology of osteoporosis[J].Med Hypotheses,2006,67(4):729-735.
  • 10Mansouritorghabeh H,Rezaieyazdi Z,Saadati N,et al.Reduced bone density in individuals with severe hemophilia B[J].Int J Rheum Dis,2009,12(2):125-129.

二级参考文献60

  • 1王义国,刘倩,王文奇,陈自平,闫明先.乙型肝炎肝硬化患者骨质疏松的临床研究[J].中华全科医师杂志,2006,5(1):26-29. 被引量：4
  • 2陈丽霞.血友病骨关节病变的物理治疗[J].继续医学教育,2006,20(30):89-93. 被引量：11
  • 3洪俊平,冷秋萍.碘伏配合湿润烧伤膏治疗褥疮的临床观察[J].护理实践与研究,2006,3(6):34-35. 被引量：7
  • 4Arita Y, Kihara S,Ouchi N, et al. Paradoxical decrease of an adipose- specific protein, adiponectin, in obesity[J]. Biochem Biophys Res Commun, 1999,257 (1) : 79 - 83.
  • 5Waki H, Yamauchi T, Kamon J. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin[J]. J Biol Chem ,2003,278(41) : 40352 - 40363.
  • 6Vasseur F,Lepretre F, Lacquemant C, et al. The genetics of adiponectin[J]. Curr Diab Rep,2003,3 : 151 - 158.
  • 7Stumvoll M, Tschritter O, Fritsche A, et al. Association of the T- G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes[J]. Diabetes,2002,51(1):37 - 41.
  • 8Yamauchi T, Kamon J, ho Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects [J].Nature,2003,423(6941) :762 - 769.
  • 9Wallis GA,Rash B,Sykes B,et al. Mutations within the gene encoding the alpha I(X) chain of type X collagen (COL10A- 1) cause metaphyseal chondrodysplasia type Sehmid but not several other forms of metaphyseal chondrodysplasia[J]. Med Genet,1996,33(6) :450 - 457.
  • 10Ouehi N,Kihara S,Arita Y, et aI. Adiponectin, an adipocyte - derived plasma protein, inhibits endothelial NF- kappaB signaling through a cAMP - dependent pathway[J]. Circulation,2000,102(11) : 1296 - 301.

共引文献22

同被引文献67

  • 1封飞虎,崔友琼.运动与儿童青少年骨健康[J].湖北体育科技,2007,26(1):54-56. 被引量：8
  • 2赵琳,安丽花,廖文君.青少年膳食钙摄入状况对骨密度的影响[J].临床儿科杂志,2007,25(10):851-852. 被引量：7
  • 3Rosen H N, Vokes T J, Malabanan A O, et al. The Official Positions of the International Society for Clinical Densitometry: Vertebral Fracture Assess ment[J]. Journal of Clinical Densitometry, 2013,16 (4) 482 - 488.
  • 4Franchini M, Mannucci P M. Past, present and fu- ture of hemophilia: a narrative review[J]. Orphanet Journal of Rare Diseases, 2012, 7(5) : 1 - 8.
  • 5Giordano P, Franchini M, Lassandro G, et al. Is- sues in pediatric haemophilia care[J]. Italian Journal of Pediatrics, 2013,39(1) 1 - 5.
  • 6Tlacuilo- Parra A, Villela- Rodriguez J, Garibaldi -Covarrubias R, et al. Bone turnover markers and bone mineral density in children with haemophilia [J]. Haemophilia the Official Journal of the World Federation of Hemophilia,2011,17(4) :657- 661.
  • 7Panagiotis A, Timoleon - Achilleas V, Maria C, et al. The effect of monthly ibandronate on bone miner- al density and bone turnover markers in patients with haemophilia A and B and increased risk for fracture [J]. Thrombosis Haemostasis, 2013,110 (2) : 257 -263.
  • 8Alioglu B, Selver B, Ozsoy H, et al. Evaluation of bone mineral density in Turkish children with severe haemophilia A: Ankara hospital experience[J]. Hae- mophilia,2012,18(1) ..69 - 74.
  • 9Roushan N, Meysamie A, Managhchi M, et al. Bone Mineral Density in Hemophilia Patients[J]. Indian Journal of Hematology Blood Transfu- sion,2014,30(4) :351 - 355.
  • 10Brown- Glabzemn U, Kissee M C, Damino M L, et al. Decreased Bone Mineral Density in Adult Patients with Hemophiliaz Clinical Significance, Prevalence and Risk Factors[J]. Journal of Coagulation Disor- ders,2011,11(2) :257 - 263.

引证文献5

二级引证文献6

中国煤炭工业医学杂志
2016年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部