妇幼保健院临床药师干预抗菌药物应用的效果分析

Effect of Clinical Pharmacist Intervention on the Rational Use of Antibiotics in Maternal and Child Health Care Hospital

目的探讨妇幼保健院临床药师干预抗菌药物应用的效果。方法对医院临床药师干预前(2011年)、干预当年(2012年)、干预后2年(2014年)的出院病历抗菌药物使用情况进行评价,并归纳日常工作模式及其持续效果。结果临床药师干预当年住院患者抗菌药物使用率(53.68%)和抗菌药物使用强度(32.82)低于干预前的70.64%和48.04(P<0.05),金额占比、联合用药不合理率均低于干预前(P<0.05),抗菌药物使用前送检率(35.67%)和限制级使用前送检率(63.41%)均高于干预前(P<0.05)。干预后医院临床抗菌药物各指标达到卫计委的要求,并能长期持续改进。结论妇幼保健院配备临床药师,通过日常有效的工作模式对抗菌药物应用进行干预,有助于临床积极、长效地合理用药。

Objective To discuss the effect of clinical pharmacists＇ intervention on rational use of antibiotics in maternal and child health care hospital. Methods The usage of antibacterial drugs in 3 periods, pre-intervention（ 2011）, intervention（ 2012） and 2 years after the intervention（ 2014） were evaluated, and the daily work patterns of clinical pharmacist and its lasting results were summarized. Results The antimicrobial rate of all hospitalized patients in intervention and pre- intervention were 53. 68% and 70. 64%, respectively with statistically significant difference（ P〈0. 05）, and in usage density, they were 32. 82 and 48. 04（ P〈0. 05）. What＇s more,the amount,combination and unrational rate were also lower than that in pre- intervention（ P〈0. 05）. On the other side,the total and limit level of antibacterial drugs germiculture rate were 35. 67% and 63. 41%,which were both higher than that in pre- intervention（ P〈0. 05）. The indexes gradually after the intervention in the clinical antibacterial drug reached the requirements of Health Development＇s planning commission,and could be improvement continuously. Conclusion Through the effective daily work patterns of antimicrobial application to intervene,clinical pharmacist in maternal and child health care hospital is helpful to rational drug use actively and continuously.