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血清DKK-1及DKK-3蛋白与膀胱癌的相关性探讨

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摘要 目的:探讨血清DKK-1及DKK-3蛋白与膀胱癌的相关性。方法:以本院36例膀胱癌患者为观察组,36名健康体检者作对照组,采用美联免疫吸附试验检测对照组和观察组术前、术后DKK-1及DKK-3蛋白水平。结果:观察组术前DKK-1明显高于术后和对照组,DKK-3术前、术后无统计学差异(P>0.05),但与对照组比较,差异有统计学意义(P<0.05);浸润性膀胱癌DKK-1术前、术后同浅表性膀胱癌比较无统计学差异(P>0.05),DKK-3术前、术后比较差异具统计学意义(P<0.05)。结论:血清DKK-1和DKK-3与膀胱癌存在一定相关性,DKK-1可作为新型肿瘤标志物,DKK-3可能参与病灶浸润、转移。
出处 《中国民族民间医药》 2016年第2期106-106,108,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词 膀胱癌 DKK-1 DKK-3
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