缬沙坦与福辛普利治疗老年原发性高血压合并高尿酸血症效果分析

Effect of valsartan and fosinopril in the treatment of elderly patients with essential hypertension and hyperuricemia

目的：探讨缬沙坦和福辛普利治疗老年原发性高血压合并高尿酸血症的临床效果。方法：选择2013年5月~2015年5月我院收治的95例老年原发性高血压合并高尿酸血症患者,随机分为两组,分别采用缬沙坦和福辛普利进行治疗,比较两组治疗效果。结果：治疗8周后,两组血压均有显著下降（P〈0.05）,但两组治疗后血压的差异并无统计学意义（P〉0.05）;缬沙坦组血尿酸水平治疗后显著降低且与福辛普利组相比,差异有统计学意义（P〈0.05）。结论：缬沙坦在治疗老年原发性高血压同时可降低血尿酸水平,值得临床推广。

Objective：To investigate the clinical effect of valsartan and fosinopril in the treatment of elderly patients with essential hypertension and hyperuricemia. Methods：95 cases of elderly patients with essential hypertension complicated with hyperuricemia were randomly divided into two groups. Two groups Were treated with valsartan and fosinopril,respectively,Compared the therapeutic effect of the two groups.Results：After 8 weeks treatment,the blood pressure of two groups of patients compared were decreased than before treatment（P0.05）.But there were no significant difference between two groups after treatment（P0.05）; Serum uric acid levels of the valsartan group after treatment decreased significantly and compared with Fosinopril group,the difference was statistically significant（P0.05）. Conclusion：Valsartan and fosinopril in the treatment of elderly patients with essential hypertension and hyperuricemia is worthy of clinical popularization and application.