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尼可地尔治疗慢性缺血性心肌病患者心力衰竭的临床疗效观察 被引量:52

Effect of Nicorandil treatment on heart function in patients with ischemic cardiomyopathy
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摘要 目的对尼可地尔治疗慢性缺血性心肌病心力衰竭患者的临床疗效进行有效性分析与评价。方法44例缺血性心肌病伴心力衰竭患者为研究对象,随机分为观察组与对照组各22例。对照组给予常规抗心衰药物治疗,观察组在常规治疗基础上加用尼可地尔片。6个月后对两组患者治疗前后左心室收缩末内径、左室舒张末内径、左心室射血分数、6分钟步行距离及再住院率进行对比分析(P<0.05)。结果两组患者治疗前后临床效果均有明显改善,尼可地尔组治疗效果显著优于常规治疗组(P<0.05)。结论慢性缺血性心肌病心力衰竭患者常规治疗基础上加用尼可地尔片,可显著改善患者心功能。 Objective Analysis and evaluation of the effectiveness of clinical treatment of nicorandil in patients with chronic ischemic cardiomyopathy heart failure.Method 44 cases of ischemic cardiomyopathy patients with heart failure patients as the research object,randomly divided into observation group and control group with 22 cases in each group.The control group was given conventional anti heart failure drug treatment,the observation group in the conventional therapy plus Nicorandil Tablets.After 6 months of two groups of patients before and after left ventricular end systolic diameter,left ventricular end diastolic diameter,left ventricular ejection fraction,6 minutes walking distance and rehospitalization rate of contrastive analysis(P0.05).Result The two groups before and after treatment in patients with clinical effect were obviously improved,the treatment effect of nicorandil group was higher than that of the conventional treatment group(P0.05).Conclusion The patients of chronic ischemic cardiomyopathy heart failure on the basis of conventional therapy plus Nicorandil Tablets,can significantly improve cardiac function.
出处 《中国临床医生杂志》 2016年第1期30-32,共3页 Chinese Journal For Clinicians
关键词 尼可地尔 缺血性心肌病 心力衰竭 Nicorandil Ischemiccardiomyopathy Heart failure
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  • 1Krzysztof G, Krzysztof M, JaroslawD, et al. Mechanisms of functional mitral regurgitation in ischemic cardiomyopathy determined by transesophageal echo-cardiography (from the surgical treatment for is- chemic heart failuretrial) [ J ]. Am J Cardiol, 2013,112 ( 11 ) : 1812- 1818.
  • 2Takeshi N, Yasuchika T, Toshiki S, et al. Usefulness of albuminuria as a prong-ostie indicator in patients with chronic heart failure see- ondary to ischemic or idiopathic dilated cardiomyopathy [ J ]. Am J Cardiol,2013,111 (8) :1180-1186.
  • 3VasilikiB, John TP, Joannis P, et al. Prognostic value of tissue Doppler right ventrieular systolie function indexes combined with plasma B-type natriuretie peptide inpatients with advanced heart fail- ure secondary to isehemie or idiopathic dilated cardiomyopathy [ J ]. Am J Cardio1,2010,105 ( 2 ) :249-255.
  • 4顾东风,黄广勇,吴锡桂,段秀芳,何江,Paul K Whelton,Stephen Mac Mahon.中国心力衰竭流行病学调查及其患病率[J].中华心血管病杂志,2003,31(1):3-6. 被引量:1277
  • 5马丹,周芝兰.卡维地洛联合尼可地尔对冠心病心肌缺血及左室舒张功能的影响[J].疑难病杂志,2012,11(9):655-657. 被引量:31
  • 6John, JV, McMurray. The European guidelines for the treatment of chronic heart failure [ Z ]. European Heart Association,2012.
  • 7王彦山,宋坤青,王莉,李红梅,高志胜.尼可地尔的临床应用进展[J].医学综述,2013,19(16):2930-2932. 被引量:22
  • 8Ishibashi Y, Takahashi N, Tokumaru A, et al. Effects of long-term nicorandil administration on endothelial function, inflammation, and oxidative stress in patients without coronary artery disease [ J]. J Car- diovasc Pharmaco1,2008 (51 ) :311-316.
  • 9Izumiya Y, Kojima S, Araki S, et al. Long-term use of oral nicorandil- stabil-izes coronary plaque in paients with stable anginapectoris [ J ].Atheroselerosis,2011 (214) :415-421.
  • 10Horinaka S, Yabe A, Yagi H, et al. Effects of nieroandil on cardiovas- cular even-ts in patients with coronary artery disease in the Japanese Coronary Artery Di-sease ( JCAD ) study [ J ]. Circulation J, 2010,74 (3) :503-509.

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