鼻渊通窍颗粒联合阿莫西林治疗急性鼻窦炎49例

Biyuan Tongqiao Granule combined with Amoxicillin in the Treatment of Acute Sinusitis for 49 Cases

目的观察分析鼻渊通窍颗粒联合阿莫西林治疗急性鼻窦炎的临床疗效。方法选取2013年5月—2014年10月收治的急性鼻窦炎患者98例,随机分为对照组49例,观察组49例。对照组患者采用阿莫西林治疗,0.5 g/次,3次/d,口服;观察组患者口服阿莫西林,方法与对照组相同,同时联合鼻渊通窍颗粒治疗,15 g/次,3次/d,热水冲服。一个疗程后对两组患者治疗的临床疗效进行观察对比和分析。结果观察组治愈率为61.2%,明显高于对照组的42.9%,差异有统计学意义(P<0.05);观察组总有效率为89.8%,明显高于对照组的69.4%,差异有统计学意义(P<0.05);观察组不良反应发生率为6.1%,略小于对照组的10.2%,差异无统计学意义(P>0.05)。结论鼻渊通窍颗粒联合阿莫西林治疗急性鼻窦炎的临床疗效较好,用药较为安全,值得推广应用。

Objective To observe the clinical effect of Biyuan Tongqiao granule combined with amoxicillin in the treatment of acute sinusitis. Methods Selecting 98 cases of patients with acute sinusitis in our hospital, and they were randomly divided into two groups. The control group took orally amoxicillin, 0.5g / time, 3 times daily. The observation group was given Biyuan Tongqiao gran-ule, 15 g / time, 3 times / D, hot water flushes the clothing on the basis of the control group. After a course of treatment, the clinical curative effect of two groups was observed and analyzed. Results The cure rate of the observation group was 61.2% which was significantly higher than 42.9% of the control group, and the difference was statistically significant（ P〈0.05）. The total effective rate of the observation group was 69.4% which was significantly higher than 69.4% of the control group, and the difference was statistically significant（P〈0.05）. The adverse reaction rate of the observation group was 6.1 % which was slightly less than 10.2% of the control group, and the difference was not statistically significant（ P〉0.05）. Conclusion Biyuan Tongqiao granule combined with amoxicillin capsules in treatment of acute sinusitis has better clinical effect, and is safe. It is worthy of popularization and application.