4Xiao Y,Hughes AL,Ando J.A genome-wide screen identifies a single beta-defensin gene cluster in the chicken:implications for the origin and evolution of mammalian defensins[J].BMC Genomic,2004,5(1):56-67.
5Gong D,Wilson P W,Bain M M,et al.Gallin:an antimicrobial peptide member of a new avian defensin family,the ovodefensins,has been subject to recent gene duplication[J].BMC Immunol,2010,11:12.
6Hellgren O,Ekblom R.Evolution of a cluster of innate immune genes(beta-defensins)along the ancestral lines of chicken and zebra finch[J].Immunome Res,2010,6:3.
7van Dijk A,Veldhuizen E J,Haagsman H P.Avian defensin[J].Vet Immunol Immunopathol,2008,124(1-2):1-18.
8van Dijk A,Veldhuizen E J,Kalkhove S I,et al.The beta-defensin gallinacin-6 is expressed in the chicken digestive tract andhas antimicrobial activity against food-borne pathogens[J].Antimicrob Agents Chemother,2007,51:912-922.
9Tollner T L,Venners S A,Hollox E J,et al.A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility[J].Sci Transl Med,2011,3(92):2003-2010.
10Ma D,Lin L,Zhang K,et al.Discovery and characterization of Coturnix chinensis avian beta-defensin 10,with broad antibacterial activity[J].J Pept Sci,2012,18:224-232.
4Tomas G. Defensin: antimicrobial peptides of innate immunity. Nature Reviews Immunology, 2003, 3:710-720.
5Hancock R E W, Diamond G. The role of cationic antimicrobial peptides in innate host defences. Trends in Microbiology, 2000, 8(9): 402-410.
6Akbari M R, Haghighi H R, Chambers .l R, Brisbin J, Read L R, Sharif S. Expression of antimicrobial peptides in cecal tonsils of chickens treated with probiotics and infected with Salmonella enterica serovar typhimurium. Clinical and Vaccine Immunology, 2008, 15(11): 1689-1693.
7Yang D, Chertov O, Bykovskaia S N, Chen Q, Buffo M J, Shogan J, Anderson M, Schroder J M, Wang J M, Howard O M, Oppenheim J J. β-Defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science, 1999, 286 (5439): 525-528.
8Hancock R E W, Lehrer R I. Cationic peptides: a new source of antibiotics. Trends Biotechnology, 1998, 16(2): 82-88.
9Oppenheim J J, Biragyn A, Kwak L W, Yang D. Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Annals of the Rheumatic Diseases, 2003, 62(Suppl. 2): 17-21.
10Hancock R E W, Patrzykat A. Clinical development of cationic antimicrobial peptides: from natural to novel antibiotics. Current Drug Targets-Infectious Disorders, 2002, 2: 79-83.