摘要
目的:观察在人工流产术后立即口服屈螺酮炔雌醇的临床效果,探讨其应用价值。方法:将400例早孕(<10孕周)要求行人工流产的健康妇女分为两组,观察组200例在人工流产术后立即服用屈螺酮炔雌醇,1片/d(含炔雌醇30μg和屈螺酮3mg),连服21d为1个周期,停药7d后开始第2个周期服药,连服3个周期;对照组术后采取除复方短效口服避孕药外的其他方法避孕。两组术后常规使用抗生素及益母草胶囊,比较两组术后出血量、出血持续时间、术后2周子宫内膜厚度、月经恢复情况、术后3个月内盆腔感染发生率及避孕效果,并观察服用屈螺酮炔雌醇后副作用发生情况。结果:观察组术后出血量、出血持续时间、盆腔感染发生率、月经恢复时间及月经量减少发生率均少于对照组(P<0.05);术后2周子宫内膜厚度优于对照组(P<0.05);避孕效果明显优于对照组(P<0.05),无严重副作用发生。结论:人工流产术后立即应用屈螺酮炔雌醇在减少术后出血、促进子宫恢复方面优势明显,避孕效果可靠,适于在流产后服务中推广。
Objective:To study the effectiveness of Drospirenone-Ethinylestradiol used after artificial abortion,and to evaluate its value of using in abortion.Methods:Total 400 patients preformed artificial abortion were divided into two groups with 200 patients in each group.In observation group,patients took Drospirenone-Ethinylestradiol tablets immediately after artificial abortion for 3 cycles,and patients in control group were given contraception except combined oral contraceptives.Both groups were given postoperative antibiotics and leonurus capsules.The following items of both groups were observed and compared:the amount and the duration of postoperative vaginal bleeding,menstruation recovery,endometrial thickness at postoperative 2 weeks,the incidence of pelvic infection in postoperative 3 months,and the contraceptive effectiveness and side effects of Drospirenone-Ethinylestradiol.Results:Compared with the control group,the amount of postoperative vaginal bleeding in observation group was less and the bleeding time was shorter,the menstruation recovered faster and the incidence of pelvic infection and spanomenorrhea was lower(P 0.05);2 weeks after abortion,endometrium was thicker in observation group,and the contraceptive effect was better in observation group(P〈0.05) without any severe adverse events.Conclusion:Drospirenone-Ethinylestradiol used immediately after artificial abortion has obvious advantage in reducing postoperative bleeding and promoting uterus repair,with reliable contraceptive effect.And it is worth to be promoted in post abortion care.
出处
《中国计划生育学杂志》
2016年第1期64-66,共3页
Chinese Journal of Family Planning
关键词
人工流产
屈螺酮炔雌醇
流产后服务
Artificial abortion
Drospirenone-Ethinylestradiol
Post abortion care