芒果苷的药理作用研究进展

Research progress of pharmacological effects of Mangiferin

芒果苷又称知母宁、芒果素,主要存在于漆树科和龙胆科植物中。因其是多酚酸类化合物,具有较强的抗氧化活性和多种药理作用。近年来,国内外大量研究报道芒果苷的各种药理学活性,包括抗糖尿病及其并发症、调节脂代谢异常、抗肿瘤、心血管保护、抗高尿酸血症、神经保护、抗氧化、抗炎、解热和镇痛、抗菌、抗病毒、抗辐射、保肝、促进骨骼发育、抗过敏和免疫调节等广泛的药理作用,具有进一步研究和开发的可能性。该文对近年来国内外芒果苷药理学作用的研究进展归纳、分析和总结,为进一步的药物研究和开发提供参考。

Mangiferin also called Chinonin or mango,is mainly extracted from the Anacardiaceae and Gentianaceae plants. As polyphenol compounds,Mangiferin shows a strong antioxidant activity and a variety of pharmacological effects. In recent years,laboratory study has identified a variety of pharmacological effects associated with Mangiferin including preventing diabetes and its complications,regulating lipid metabolism abnormalities,antitumor,cardiovascular protection,anti hyperuricemia,neuroprotection,anti oxidation, anti-inflammation, antipyresis and analgesia,anti-bacteria and antivirus,antiradiation,liver protection,promoting skeletal growth,anti allergy and immune regulation,etc. In this paper,the research progress of pharmacological effects of Mangiferin is reviewed,analyzed and summarized in order to provide reference for further research and development.