四维超声用于胎儿畸形产前诊断的价值分析

The Analysis of Value of Applying Four-dimensional Ultrasound to Fetal Malformation Prenatal Screening

目的：对四维超声用于胎儿畸形产前诊断的价值进行评价分析,为今后的临床诊断工作提供可靠的参考依据.方法：抽取在2012年1月-2014年12月间某院收治的接受产前畸形筛查的孕妇2108例,产前产妇均接受了二维超声和四维超声检查,以胎儿分娩、引产结果为依据,对单独二维超声、四维超声检查结果与二维超声联合四维超声检查结果进行评价.结果：经统计发现,四维超声在胎儿畸形诊断中的特异性、准确性均较二维超声高,但是无明显统计学意义（P 〉0.05）;二维超声与四维超声联合应用的诊断特异性、敏感性和准确性均较两者单独应用时高（P 〈0.05）.结论：在胎儿畸形的产前筛查中,二维超声、四维超声及其联合应用的临床价值显著,值得关注并推广.

Objective:To evaluate the value of applying four-dimensional ultrasound to fetal malformation prenatal screening and provide reference for future clinical diagnosis.Methods:Select 2108 cases of pregnant women who received fetal malformation prenatal screening in a hospital during the period from January 2012 to December 2014.All the prenatal pregnant women received two-dimensional and four-dimensional ultrasound examination.Taking fetal delivery and induction results as criteria,evaluate the results of two-dimensional ultrasound examination,four-dimensional ultrasound examination,and combined two-dimensional and four-dimensional ultrasound examination.Results:Statistic analysis showed that four-dimensional ultrasound had higher accuracy and specificity than two-dimensional ultrasound examination in fetal malformation prenatal screening,however,the difference was not significant(P>0.05);combined two-dimensional and four-dimensional ultrasound examination had higher accuracy and specificity than two-dimensional ultrasound examination or four-dimensional ultrasound examination,the difference was statistically significant(P <0.05).Conclusion:In fetal malformation prenatal screening,two-dimensional ultrasound examination,four-dimensional ultrasound examination,and combined two-dimensional and four-dimensional ultrasound examination had significant clinical value and are worth to be promoted.