摘要
目的使用电感耦合等离子体质谱（ICP-MS）仪,建立天舒胶囊中Cu、As、Pb、Cd、Hg 5种重金属元素的测定方法.方法：样品经过微波消解处理后,采用外标法,以ICP-MS进行测定.结果：各元素线性关系良好（r〉0.9990）,最低检测限为（0.0014-0.8237）μg·L^-1,回收率为98.4%-114.1%.结论：该方法准确、简便、快速、灵敏,适用于天舒胶囊内容物中重金属的含量测定.
Objective: To provide a method for the simultaneous analysis of five heavy metals, including Cu, As, Pb, Cd and Hg, in Tian Shu capsules. Methods: Five heavy metals in Tian Shu capsules were determined by a method of inductivity coupled plasma-mass spectrometry with microwave-assisted digestion.Results: The correlation coefficients were better than 0.999. The method detection limits for all target elements were in the range of(0.0014-0.8237) μg·L-1, and the recoveries ranged in 98.4%-114.1%. Conclusion: This method is accurate, convenient, rapid and highly sensitive and can be applied to determine the five heavy metals, including Cu, As, Pb, Cd and Hg, in Tian Shu capsules.
出处
《药学与临床研究》
2016年第1期23-25,共3页
Pharmaceutical and Clinical Research
基金
国家科技部"重大新药创制"项目:偏头痛治疗药物天舒胶囊大品种技术改造(2012ZX09201201-002)
