摘要
目的:报道我院肾病综合征(NS)抗凝药物的合理应用情况,探讨药师在抗凝治疗中的作用。方法:以几例NS的抗凝治疗来阐明合理用药。根据患者症状、体征、凝血常规及其他反映高凝状态的指标,结合抗凝药物的药理作用机制、药效/药动学特性及应用时潜在的风险,对抗凝药物的选择、用法、更换、过渡及联用进行探讨。结果与结论:抗凝方案的正确调整对治疗起到了良好效果。
ABSTR ACT Objective: To analyze the use of anticoagulant drugs in patients with nephrotic syndrome(NS), and to investigate the role of pharmacists in anticoagulant treatment. Methods: Typical cases of NS using conventional anticoagulant drugs were used as samples. Considering patients' symptoms, signs, coagulation routine and other indicators reflecting the hypercoagulable state, the choice, replacement, transition and combination of anticoagulant drugs were checked based on their pharmacological mechanism of action,pharmacodynamic/pharmacokinetic properties, advantages and disadvantages as well as their potential risks of application. Results and Conclusion: Adjusted treatment programs improved therapeutic effects.
出处
《药学与临床研究》
2016年第1期75-78,共4页
Pharmaceutical and Clinical Research
关键词
抗凝
低分子肝素
尿激酶
双嘧达莫
阿魏酸哌嗪
华法林
氯吡格雷
Anticoagulant
Low molecular weight heparin
Urokinase
Dipyridamole
Piperazine ferulate
Warfarin
Clopidogrel
