论从丰富环境改善认知构建大鼠“思”模型:学习记忆与“脾主思”

Discussion on Rat Model of Environmental Enrichment Improving Cognition:Learning and Memorizing Mimicking Thought of Spleen

"脾在志为思"是中医情志理论的重要组成部分,是情志活动的核心环节。目前对"脾主思"研究的临床和基础研究严重不足。虽然怒、恐等情志的动物模型已经建立,但思的动物模型尚未见报道。丰富环境可改善大鼠的认知,增强学习和记忆,模拟思考过程,是脾主思在大鼠身上的体现。因此作者提出丰富环境刺激可改善大鼠认知过程促进思考(学习记忆)的假说,以此为基础建立"思"的动物模型。

The theory that the spleen governs thought is a elementary part of the emotion doctrine in TCM and plays a core role in emotional activities. However,the theory remains under- researched clinically and fundamentally. Although vary animal models on the anger and fear have been well established,no model on the thought（ Si） has been reported. Environmental enrichment is believed to improve cognition,enhance memory,mimic the process of thinking on rat,i. e. the project of the theory. Therefore,the authors hypothesized that environmental enrichment could stimulate a rat and improve the process of cognition including thinking,learning and memorializing,based on which a rat model of thought（ Si） would be established.