糖尿病肾病治疗中益肾化湿颗粒与贝那普利联合应用的价值分析

Analysis on Application Value of Benazepril Hydrochloridec Combined with Yishen Huashi Particles in Diabetic Nephropathy

目的:总结联合益肾化湿颗粒及贝那普利治疗糖尿病肾病(DN)的临床应用价值。方法:以随机数字表法将80例DN患者随机分为两组,每组40例。以在常规降糖的同时接受贝那普利治疗者为对照组,以在常规降糖的同时接受联合益肾化湿颗粒及贝那普利治疗者为观察组。对比两组接受治疗后的临床治疗效果。结果:两组入组时FPG、2h BG、Cr、BUN及24 hm Alb水平比较,未见统计学差异(P>0.05),而在接受治疗4周后,观察组FPG、2 h BG、Cr、BUN及24 hm Alb水平明显低于对照组(P<0.05)。对照组治疗总有效率为70.00%,观察组治疗总有效率为90.00%,观察组治疗总有效率明显高于对照组(P<0.05)。两组治疗期间副作用发生率比较,无统计学差异(P>0.05)。结论:DN治疗中联合益肾化湿颗粒及贝那普利可在不降低患者治疗效果的同时,有效的通过临床治疗效果。

Objective： To summarize the application value of Benazepril Hydrochloridec combined with Yishen Huashi Particles in diabetic nephropathy. Methods： With random number table method,80 patients with DN were randomly divided into two groups,40 cases in each group. Control group was treated with routine Benazepril Hydrochloridec and observation group received routine Benazepril Hydrochloridec and Yishen Huashi Particles. We compared the two groups＇ clinical therapeutic effect after treatment.Results： There was no statistical difference of FPG,2 h BG,Cr,BUN and 24 hm Alb horizontal between the two groups before treatment（ P〉0. 05）,but after 4 weeks treatment,the FPG,2 h BG,Cr,BUN and 24 hm Alb levels of observation group were significantly lower than the control group＇s（ P〈0. 05）. The total effective rate of control group was 70. 00% and the total effective rate of observation group was 90. 00%. The observation group＇s was obviously higher than that of control group（ P〈0. 05）. There was no statistical difference of side effects incidence between the two groups（ P〉0. 05）. Conclusion： Benazepril Hydrochloridec and Yishen Huashi Particles can treat the DN and not reduce the effectiveness at the same time.