两种脂肪纯化方法对自体脂肪移植隆乳术的临床效果影响

Clinical effects of two different purification methods on augmentation mammaplasty by autologous fat transfer

目的:探讨两种不同脂肪纯化方法对自体脂肪移植隆乳术脂肪存活率的影响,并对比两者术后的临床效果。方法:选取2012年6月-2015年6月在陕西省汉中市中心医院烧伤整形美容科接受自体脂肪移植隆乳的患者116例,分为离心组及静置组,每组58例,在各接受2次自体脂肪颗粒注射移植术后6个月时,记录受术者术前术后乳房体积、隆起值和保持率、两次的补脂量,脂肪存活率、术后患者满意度以及两组乳房外形变化进行综合评价。结果:离心组的隆起值和保持率在术后1、3、6个月均高于静置组(均P<0.05);离心组移植术后6个月两侧乳房脂肪体积均显著高于静置组(P<0.05);离心组左右双侧乳房脂肪存活率高于静置组(P<0.001)。离心组经两次脂肪注射移植后满意率优于静置组(P<0.05)。结论:自体脂肪移植隆乳术临床效果确切可靠,抽取的脂肪颗粒釆用离心机适当的离心后再注射移植,较单纯的静置纯化脂肪法乳房隆起效果好、脂肪存活率和满意度高,值得临床推广。

Objective In this study, we compared the clinical effects of two different purification methods on breast augmentation by autologous fat transfer. Methods One hundred and sixteen patients from June 2012 to June 2015 with breast augmentation by autologous fat transfer were selected from department of Plastic Surgery of Hanzhong Central Hospital of Shaanxi and randomly divided into centrifugal group and static group, each with 58 cases. The results were evaluated by breast volume, breast height（length from the nipple to the anterior chest wall）, retention rate, survival rate of fat, patient＇s satisfaction and change in breast shape 6 months after transplantation. Results Compared to the static group, breast height and retention rate at 1, 3 and 6 months after transplantation were higher in centrifugal group（all P 0.05）. The breast volume on both sides of centrifugal group after 6 months was significantly higher than the static group（P0.05）. The survival rate of fat was higher in the centrifugal group compared with static group（P 0.001）. Finally, patient＇s satisfaction in the centrifugal group was significantly higher than static group（P0.05）. Conclusion Based on our findings, compared with static purification, appropriate centrifugal purification significantly increased breast height, improved survival rate of fat and enhanced patient＇s satisfaction, worthy to be popularized.