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首发精神分裂症听感觉门控P50、P300与PANSS的相关性研究 被引量:3

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摘要 目的:探讨首发精神分裂症患者听感觉门控 P50、P300与PANSS之间的相关性. 方法:采用配对听觉条件、测试刺激范式与PANSS对60名首发精神分裂症患者和60名健康常人进行检测,并进行对比分析. 结果:患者组听感觉门控P50抑制、明显高于对照组( P<0 .01 ) , P300明显低于于对照组( P<0 .01 );患者组听感觉门控P50抑制与PANSS无对比性,但P300与PANSS之间有相关性. 结论:(1)首发精神分裂症患者P50存在异常,反映其感觉门控功能存在缺损;首发精神分裂症患者P300存在异常,反映其高级认知功能受损.(2)首发精神分裂症患者存在认知功能损害与额叶功能缺陷,反映出可能存在不同的神经发生机制.
出处 《中国伤残医学》 2016年第2期31-33,共3页 Chinese Journal of Trauma and Disability Medicine
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