多囊卵巢综合征患者临床内分泌代谢改变对子宫内膜病变的影响

The Effect of Endometrial Lesion of Patients With Polycystic Ovarian Syndrome by Endocrinology and Metabolism Changed

目的探讨多囊卵巢综合征患者的临床内分泌代谢改变对子宫内膜病变的影响。方法选取我院收治的多囊卵巢综合征患者60例,采用组织学方法检测患者的子宫内膜病理改变,观察胰岛素和血糖与不同子宫内膜病理类型的关系。结果无排卵型内膜率高于排卵型内膜率;无排卵型内膜患者在空腹时的血清胰岛素水平与糖负荷60 min、120 min后的血清胰岛素水平以及曲线下面积均高于排卵型内膜患者,P<0.05,差异具有统计学意义。结论胰岛素改变了多囊卵巢综合征患者的子宫内膜病变,应进行及早的预防。

Objective To discuss the effect of endometrial lesions changed by Endocrinology and Metabolism of polycystic ovarian syndrome.Methods Selected 60 cases with polycystic ovarian syndrome in our hospital.To inspected the pathologic change of endometrium as the histology method,and to observed the relationship between the insulin,blood glucose and different pathology types of endometriums.Results The rate of ovulation was higher than that of ovulation type,The serum insulin level and that glycemic loaded for 60 minutes and 120 minutes,and area under the curve of the endometrium without ovulation was significantly greater than the endometrium with ovulation,P〈0.05,was difference had statistically significance.Conclusion The endometrial lesions of patients with polycystic ovarian syndrome has been changed by insulin.