小儿特发性矮小症治疗中重组人生长激素应用的价值探究

To Explore the Value of Recombinant Human Growth Hormone in Treatment of Children With Idiopathic Nanism

目的探讨重组人生长激素在小儿特发性矮小症治疗中的临床应用效果。方法将我院2013年1月-2014年1月进行小儿特发性矮小症治疗的60例患儿随机分成对照组和治疗组。对照组行营养支持及补充钙和赖胺肌醇维生素B_（12）,治疗组在此基础上予以重组人生长激素进行治疗,比较两组患者的治疗效果。结果治疗后,治疗组生长速度高于对照组,且骨龄、骨龄对应的身高标准分值及成年身高预测等变化均优于对照组（P〈0.05）。结论在小儿特发性矮小症患儿中运用重组人生长激素进行治疗具有较高的临床效果,可有效增加患儿的生长速度,促进健康成长,有效保障生活质量。

Objective To explore the Value of recombinant human growth hormone in treatment of children with idiopathic nanism.Methods Selected 60 cases with idiopathic nanism from January 2013 to January 2014 in our hospital,which were randomly divided into the control group and the treatment group.The control group underwent nutritional support,as well as calcium and vitamin B_（12） amine inositol treatment,the treatment group received recombinant human growth hormone on the basis of treatment,compared the treatment effect between the two groups of patients.Results After treatment,the treatment group was higher growth rate and bone age,bone age corresponding height standard scores and other changes predicted adult height than the control group（P〈0.05）.Conclusion Children with idiopathic nanism recombinant human growth hormone treatment has a high clinical effect,can effectively increase the growth rate of children,to promote the healthy growth of children,effective protection of the quality of life,deserve wide promotion.