阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效及安全性分析

Analysis the Security and Clinical Effect of Azithromycin Sequential Therapy for Children With Mycoplasma Pneumonia

目的对阿奇霉素序贯疗法治疗小儿支原体肺炎的临床效果和安全性进行探究。方法选择我院收治的106例小儿支原体肺炎患儿作为研究对象,将其随机分为治疗组和对照组,每组53例。治疗组以阿奇霉素序贯疗法对患儿进行治疗,对照组以红霉素对患儿进行治疗,比较两组患儿的临床疗效和不良反应发生情况。结果治疗组总有效率90.57%,高于对照组79.25%;不良反应的发生情况9.43%,少于对照组24.53%,P<0.05,差异具有统计学意义。结论阿奇霉素序贯疗法应用于小儿支原体肺炎具有良好的临床效果,不良反应发生率低,安全性高。

Objective To explore security and clinical effect of azithromycin sequential therapy for children with mycoplasma pneumonia.Methods Selected 106 cases of children with mycoplasma pneumonia in our hospital as the research object,which were randomly divided into the treatment group and the control group,53 cases in each group.The treatment group with azithromycin sequential therapy for children with treatment,the control group of children by erythromycin treatment,compared the clinical efficacy and adverse reaction of two groups.Results The treatment group total effective rate was 90.57% higher than the control group 79.25%,The occurrence of adverse reaction cases was 9.43% lesser than the control group 24.53%,P〈0.05,was difference had statistically significance.Conclusion Azithromycin sequential therapy application without mycoplasma pneumonia has good clinical effect,low incidence of adverse reactions,high safety.