伐昔洛韦联合咪喹莫特治疗67例生殖器疱疹疗效观察

Observation Curative Effect of Valacyclovir Combine With Imiquimod in Treatment of 67 Cases With Genital Herpes

目的探究与分析伐昔洛韦联合咪喹莫特治疗生殖器疱疹的疗效。方法选取我院収治的134例生殖器疱疹患者,采取随机数字表法分为单独用药组与联合用药组,每组67例,单独用药组仅口服伐昔洛韦,联合用药组在其基础上加用咪喹莫特,对比两组患者临床疗效。结果联合用药组随访12周的复发率低于单独用药组,P<0.05,差异具有统计学意义。结论采用伐昔洛韦联合咪喹莫特治疗生殖器疱疹的临床疗效显著,近期复发率较低。

Objective To explore and analysis valaciclovir joint imiquimod treatment of genital herpes treatment.Methods Selected 134 cases in our hospital patients with genital herpes,randomly were divided into the separate groups and the drug combination group,67 cases in each group,the separate group only received oral medication valacyclovir,combination therapy group its based on the use of imiquimod clinical efficacy compared two groups of patients.Results The combined group 12 weeks of followup recurrence rate is lower than the single drug group,P〈0.05,was difference had significance statistically.Conclusion The clinical efficacy of valacyclovir joint imiquimod treatment of genital herpes significantly lower relapse rate recently.