摘要
干细胞移植治疗视网膜退行性疾病的研究近年来受到广泛关注,这些研究通过移植胚胎干细胞、脐带干细胞、骨髓来源干细胞以及诱导多能干细胞等促进受损视网膜修复并改善视功能,个别研究已进入临床试验阶段,为视网膜色素变性和年龄相关性黄斑变性等患者带来复明的希望。本文对这一领域的研究现状予以综述,并就其发展前景和面临的挑战予以讨论。
Stem cell-based therapies for retinal degenerative diseases are underway. In recent studies, kinds of stem cells such as embryonic stem cell, umbilical cord stem cell, bone marrow-derived stem cells and induced pluripotent stem cell have been pursued to repair the damage of retina and improve visual function, and some studies have entered into clinical trials which brought hope to regain sight for patients suffering from retinitis pigmentosa and age related macula degeneration. In this review, we summarized the progress of stem cell-based approaches for treating retinal degenerative diseases and discussed the prospect and challenges in this field.
出处
《中国中医眼科杂志》
2015年第6期444-447,共4页
China Journal of Chinese Ophthalmology
基金
国家自然科学基金资助项目(81473736)
关键词
视网膜退行性病变
干细胞治疗
retinal degenerative diseases
stem cell-based therapy
